Gout is disease that predominantly occurs in men and post-menopausal women. Hyperuricemia which is caused by urate monohydrate crystal deposition in joints and kidneys is the underlying metabolic disorder in gout. The deposition of the urate crystals causes the inflammation of the joints. It has been linked to the development of other illness like hypertension, cancer, hyperlipidemia, diabetes and obesity. Xanthine oxidase is an enzyme found in the liver and the small intestinal mucosa, that oxidizes hypoxanthine to xanthine and xantine to uric acid which leads to hyperuricemia. Allopurinol, the commercially available drug for hyperuricemia and gout, is a purine analog that inhibits xanthine oxidase. It is very effective but it comes with a lot of serious side effects from allergic reactions to renal failure and liver malfunction It is for this reason that novel XO inhibitor alternatives must be discovered.